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Public perceptions of nicotine have long been marred by its association with harmful constituents of tobacco smoke, despite the substantial evidence showing that nicotine is not responsible for the many non-communicable diseases caused by tobacco smoking. Nicotine, safely administered, has long been accepted by governments and health authorities, including the WHO, as a valuable tool to aid smoking cessation in the form of nicotine replacement therapy. Joining us today is Michael Kariuki, a consultant pediatrician and epidemiologist from Kenya, to discuss the therapeutic applications of nicotine and the vital role of safer nicotine products in aiding smoking cessation.